Peptide toxin components of Amanita exitialis basidiocarps
نویسندگان
چکیده
منابع مشابه
Illumina-based de novo transcriptome sequencing and analysis of Amanita exitialis basidiocarps.
Amanita exitialis is a lethal mushroom that was first discovered in Guangdong Province, China. The high content of amanitin in its basidiocarps makes it lethal to humans. To comprehensively characterize the A. exitialis transcriptome and analyze the Amanita toxins as well as their related gene family, transcriptome sequencing of A. exitialis was performed using Illumina HiSeq 2000 technology. A...
متن کاملColocalization of amanitin and a candidate toxin-processing prolyl oligopeptidase in Amanita basidiocarps.
Fungi in the basidiomycetous genus Amanita owe their high mammalian toxicity to the bicyclic octapeptide amatoxins such as α-amanitin. Amatoxins and the related phallotoxins (such as the heptapeptide phalloidin) are encoded by members of the "MSDIN" gene family and are synthesized on ribosomes as short (34- to 35-amino-acid) proproteins. Antiamanitin antibodies and confocal microscopy were used...
متن کاملProduction and characterization of Amanitin toxins from a pure culture of Amanita exitialis.
Amanita exitialis Zhu L. Yang and T.H. Li is a lethal mushroom species recently isolated in Guangdong Province, China. In this report, a pure culture of this species was obtained for the first time. To confirm the identity of the pure culture, the internal transcribed spacer regions of the nuclear ribosomal DNA of the pure culture and of a typical fruiting body of the species were sequenced and...
متن کاملRibosomal biosynthesis of the cyclic peptide toxins of Amanita mushrooms.
Some species of mushrooms in the genus Amanita are extremely poisonous and frequently fatal to mammals including humans and dogs. Their extreme toxicity is due to amatoxins such as alpha- and beta-amanitin. Amanita mushrooms also biosynthesize a chemically related group of toxins, the phallotoxins, such as phalloidin. The amatoxins and phallotoxins (collectively known as the Amanita toxins) are...
متن کاملFour Newly Recorded Amanita Species in Korea: Amanita sect. Amanita and sect. Vaginatae
We collected nearly 70 specimens of Amanita species during a diversity study of Korean mushrooms conducted in 2012. In this study, we primarily investigated 23 Amanita specimens belonging to sections Amanita and Vaginatae. Based on sequence data of the internal transcribed spacers and partial large subunit of ribosomal RNA and morphological characteristics, we identified the following 15 phylog...
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ژورنال
عنوان ژورنال: Mycologia
سال: 2011
ISSN: 0027-5514,1557-2536
DOI: 10.3852/10-319